Neuronal proto-oncogene expression in the pharmacological assessment of the synaptic mechanisms of the hippocampus in rats.

نویسنده

  • Réka Szakács
چکیده

2005 2 Animum rege, qui nisi paret, imperat. distribution and neuronal localization of c-fos protein in the rat hippocampus following 4-aminopyridine seizures.competitive NMDA receptor antagonists moderate seizure-induced c-fos expression in the rat cerebral cortex. Z.: Alterations of seizure-induced c-fos expression in the rat cerebral cortex following dexamethasone treatment. (submitted) V.fos protein in the rat forebrain following 4-aminopyridine seizures. Cephal. Hung. Abstract Booklet: N-10. neurons in the rat hippocampus after 4-aminopyridine-induced seizures. 5-HT 5-hydroxy-tryptamin, serotonin AD Alzheimer's disease AGPC acid guanidium thiocyanate-phenol-chloroform AMPA Į-amino-3-hydroxy-5-methyl-4-isoxazole propionate ANOVA analysis of variance AOI area of interest AP-1 activator protein 1 4-AP 4-aminopyridine AP5 2-amino-5-phosphonovaleric acid AP7 2-amino-7-phosphonoheptanoic acid CA cornu Ammonis cAMP 3',5'-cyclic adenosine monophosphate c-fos cellular proto-oncogene CNS central nervous system CRE cAMP response element CREBP cAMP response element binding protein DAB diaminobenzidine tetrahydrochloride DG dentate gyrus DNA deoxyribonucleic acid EEG electroencephalography GABA gamma aminobutyric acid GAD glutamic acid decarboxylase GADPH glyceraldehyde 3-phosphate dehydrogenase GluR glutamate receptor GTCS generalized tonic-clonic seizures GTP guanosine triphosphate IgG immunoglobulin G LSD lysergic acid diethylamide LTD long-term depression LTP long-term potentiation mRNA messenger ribonucleic acid Ni-DAB nickel-containing diaminobenzidine tetrahydrochloride NMDA N-methyl-D-aspartate PAP peroxidase-antiperoxidase PBS phosphate-buffered saline PCP phencyclidine PCR polymerase chain reaction PV parvalbumin RT reverse transcription SEM standard error of the mean 6 CONTENTS

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin

Objective(s): There are few reports have demonstrated the effect of a change-in-light experience on the structure and function of hippocampus. A change-in-light experience also affects the circadian pattern of melatonin secretion. This study aimed to investigate developmental effect of exogenous melatonin on synaptic plasticity of hippocampus of light deprived rats. Materials and Methods: The ...

متن کامل

Proteome Analysis of Rat Hippocampus Following Morphine-induced Amnesia and State-dependent Learning

Morphine’s effects on learning and memory processes are well known to depend on synaptic plasticity in the hippocampus. Whereas the role of the hippocampus in morphine-induced amnesia and state-dependent learning is established, the biochemical and molecular mechanisms underlying these processes are poorly understood. The present study intended to investigate whether administration of morphine ...

متن کامل

Proteome Analysis of Rat Hippocampus Following Morphine-induced Amnesia and State-dependent Learning

Morphine’s effects on learning and memory processes are well known to depend on synaptic plasticity in the hippocampus. Whereas the role of the hippocampus in morphine-induced amnesia and state-dependent learning is established, the biochemical and molecular mechanisms underlying these processes are poorly understood. The present study intended to investigate whether administration of morphine ...

متن کامل

GABA-mediated membrane oscillations as coincidence detectors for enhancing synaptic efficacy in the developing hippocampus

Spontaneously occurring neuronal oscillations constitute a hallmark of developmental networks. They have been observed in the retina, neocortex, hippocampus, thalamus and spinal cord. In the immature hippocampus the so-called ‘giant depolarizing potentials’ (GDPs) are network-driven membrane oscillations characterized by recurrent membrane depolarization with superimposed fast action potentials...

متن کامل

The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats

Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies. Any pharmacological intervention in this period may result in structural, functional or behavioral abnormalities. In this study, sodium thiopental a GABA mimetic drug was a...

متن کامل

GABA-mediated membrane oscillations as coincidence detectors for enhancing synaptic efficacy in the developing hippocampus

Spontaneously occurring neuronal oscillations constitute a hallmark of developmental networks. They have been observed in the retina, neocortex, hippocampus, thalamus and spinal cord. In the immature hippocampus the so-called ‘giant depolarizing potentials’ (GDPs) are network-driven membrane oscillations characterized by recurrent membrane depolarization with superimposed fast action potentials...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Ideggyogyaszati szemle

دوره 61 5-6  شماره 

صفحات  -

تاریخ انتشار 2008